Federal Funding (United States)
Centers for Disease Control and Prevention (CDC)
In partnership with other centers at CDC, the National Center for Injury Prevention and Control funds Tribal Epidemiology Centers, tribes, and tribal-serving organizations to support regional strategic plan priority areas to address tribal opioid overdose prevention, including epidemiologic surveillance and public health data infrastructure, implementation of evidence-based health systems interventions, and innovative community-based strategies. NCIPC also funds national partners to provide training and technical assistance to tribes implementing overdose prevention initiatives. Learn More
New: Urban Indian Organization Funding Opportunity
Application due January 16, 2026
Apply at https://redcap.link/UIO-App.
Seven Directions at the University of Washington, Safe States, National Network of Public Health Institutes (NNPHI), and National Council of Indian Health (NCUIH) have been funded by the U.S. Centers for Disease Control (CDC) to support building capacity within Urban Indian Organizations to design and implement culturally grounded overdose prevention projects.
The Overdose Prevention projects will focus on overdose prevention in urban Indian communities. For example, projects could include developing a plan for a community needs assessment, identifying and preparing cultural components needed to support overdose prevention efforts, community outreach to raise overdose awareness, or other activities aimed at reducing the risk of overdose for American Indian and Alaska Native community members living in urban areas. Cultural components could include traditional healing, ceremony, or other cultural practices.
Five to seven grants are available.
Amount: up to $45,000. Amount will depend on activities proposed.
Information sessions to answer questions:
Thursday, December 11, 12pm PT/3pm ET
Thursday January 8, 12pm PT/3pm ET
Register for the Zoom Link here:
Or via https://bit.ly/UIO-Hour
Meeting ID: 922 9392 3311
Project Timeline:
– December 2025: Application launches
– January 16th, 2026: Application closes
– Between January 16th – February 4th: Interviews with applicant
– February 6th 2026: Applicants notified of award selection
– March 1st to June 30th, 2026: Project Implementation Period
– July 2026 (date TBA): Invitation to attend the AI/AN Injury and Violence Prevention Conference in Green Bay, WI. There will be a UIO Overdose Prevention grant recipients meeting at this conference.
Seven Directions will offer targeted technical assistance, including individual project consultations, assistance in developing your project’s detailed scope of work and budget justification, and ongoing training resources throughout your project. Seven Directions will meet with you monthly to discuss and to support progress on your project. NCUIH will provide training throughout the project period on topics such as overdose prevention approaches in American Indian and Alaska Native communities. NNPHI will administer the grant and provide support to address any fiscal considerations related to the proposed project.
Eligibility:
Urban Indian Organization – native-led community-based organization or community that provides social and community services and/or represents American Indian and/or Alaska Native people living in urban areas in the United States. Demonstrates a need for substance misuse and overdose prevention in their urban area.
Note: This program cannot fund research and clinical supplies or other materials that would be typically covered through a SAMHSA grant (e.g., Narcan/naloxone, fentanyl testing strips, syringes). Furthermore, due to the length of the grant period, this program cannot be used to hire new personnel or staff.
How to Apply:
Please complete the application: https://redcap.link/UIO-App.
Please provide major contact information for your organization, scope of work, budget, budget justification and contacts from your administration and finance team.
If you have questions about the program or application process, please contact Domin Chan, at Seven Directions, at [email protected]. For budget or contract-related questions, contact Amanda Franklin, at NNPHI at [email protected].
Substance Abuse and Mental Health Services Administration (SAMHSA)
SAMHSA’s Tribal Opioid Response Grant funds Tribal communities to address the opioid crisis by increasing access to culturally appropriate and evidence-based treatment, prevention, and recovery services and resources. Tribal grantees use TOR grants for a broad range of activities, including the development of infrastructure and strengthening of workforce capacity through training to integrate MAT in their health and service delivery programs.
Indian Health Services (IHS)
The IHS Office of Clinical and Preventive Services, Division of Behavioral Health funds Tribes, Tribal organizations, and Urban Indian organizations (UIOs) to combat the substance abuse and suicide issues affecting Indian Country.
Bureau of Justice Assistance (BJA) (Department of Justice)
The Bureau of Justice Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP) provides financial and technical assistance to states, units of local government, and Indian tribal governments to develop, implement, or expand comprehensive efforts to identify, respond to, treat, and support those impacted by illicit opioids, stimulants and other drugs.
National Institutes of Health (NIH)
The National Institutes of Health (NIH) funds biomedical and public health research. The NIH is made up of 27 Institutes and Centers, including the National Institute on Drug Abuse (NIDA), which funds research on substance use and addiction, and the National Institute on Alcohol Abuse and Alcoholism (NIAAA), which funds research on the impact of alcohol use on human health and well-being.
Health Resources and Services Administration (HRSA)
The Health Resources and Services Administration Rural Communities Opioid Response Program (RCORP) funds programs to treat and prevent Opioid Use Disorder for people in rural areas.
Non-Governmental Organizations
Robert Wood Johnson Foundation
The Robert Wood Johnson Foundation funds a wide array of research and initiatives focused on achieving health equity.
Foundation for Opioid Response Efforts
The Foundation for Opioid Response Efforts (FORE) funds projects in the areas of professional education, payer & provider strategies, policy initiatives, and public awareness for ending the opioid crisis.
Opioid Litigation Settlements
For the latest information regarding the Tribal Opioid Litigation Settlements, please refer to the links below.